Mechanisms of Candida biofilm drug resistance.

@article{Taff2013MechanismsOC,
  title={Mechanisms of Candida biofilm drug resistance.},
  author={Heather T. Taff and Kaitlin Faye Mitchell and Jessica A. Edward and David R Andes},
  journal={Future microbiology},
  year={2013},
  volume={8 10},
  pages={
          1325-37
        }
}
Candida commonly adheres to implanted medical devices, growing as a resilient biofilm capable of withstanding extraordinarily high antifungal concentrations. As currently available antifungals have minimal activity against biofilms, new drugs to treat these recalcitrant infections are urgently needed. Recent investigations have begun to shed light on the mechanisms behind the profound resistance associated with the biofilm mode of growth. This resistance appears to be multifactorial, involving… CONTINUE READING
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