Mechanisms of CNS myelin inhibition: evidence for distinct and neuronal cell type specific receptor systems.

@article{Giger2008MechanismsOC,
  title={Mechanisms of CNS myelin inhibition: evidence for distinct and neuronal cell type specific receptor systems.},
  author={Roman J Giger and Karthik Venkatesh and Onanong Chivatakarn and Stephen J. Raiker and Laurie A Robak and Thomas Hofer and Hakjoo Lee and Christoph Rader},
  journal={Restorative neurology and neuroscience},
  year={2008},
  volume={26 2-3},
  pages={97-115}
}
Following injury to the adult mammalian central nervous system, regenerative growth of severed axons is very limited. The lack of neuronal repair is often associated with significant functional deficits, and depending on the severity of injury, may result in permanent paralysis distal to the site of injury. A detailed understanding of the molecular mechanisms that limit neuronal growth in the injured spinal cord is an important step toward the development of specific strategies aimed at… CONTINUE READING
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