Mechanisms of Brain Signaling During Sepsis

  title={Mechanisms of Brain Signaling During Sepsis},
  author={Najla Akrout and Tarek Sharshar and Djillali Annane},
  booktitle={Current neuropharmacology},
Brain signaling is a crucial event for the body to mount an appropriate response to invading microorganisms. Pro-inflammatory cytokines are released from infected tissues and reach key structures in the brain via the circumventricular organs, areas of damaged blood brain barrier or they cross actively the blood brain barrier using specific carriers… CONTINUE READING