Mechanisms of B-Cell Oncogenesis Induced by Epstein-Barr Virus

@inproceedings{Saha2019MechanismsOB,
  title={Mechanisms of B-Cell Oncogenesis Induced by Epstein-Barr Virus},
  author={Abhik Kumar Saha and Erle S Robertson},
  booktitle={Journal of virology},
  year={2019}
}
Epstein-Barr virus (EBV) is a ubiquitous gammaherpesvirus which asymptomatically infects the majority of the world population. Under immunocompromised conditions, EBV can trigger human cancers of epithelial and lymphoid origin. The oncogenic potential of EBV is demonstrated by in vitro infection and transformation of quiescent B cells into lymphoblastoid cell lines (LCLs). These cell lines, along with primary infection using genetically engineered viral particles coupled with recent… CONTINUE READING

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