Mechanisms of Antiaddictive Actions of Ibogaine a

  title={Mechanisms of Antiaddictive Actions of Ibogaine a},
  author={S. Glick and I. M. Maisonneuve},
  journal={Annals of the New York Academy of Sciences},
  • S. Glick, I. M. Maisonneuve
  • Published 1998
  • Chemistry, Medicine
  • Annals of the New York Academy of Sciences
  • ABSTRACT: Ibogaine, an alkaloid extracted from Tabemanthe iboga, is being studied as a potential long‐acting treatment for oploid and stimulant abuse as well as for alcoholism and smoking. Studies in this laboratory have used animal models to characterize ibogaine's interactions with drugs of abuse, and to investigate the mechanisms responsible. Ibogaine, as well as its metabolite, noribogaine, can decrease both morphine and cocaine self‐administration for several days in some rats; shorter… CONTINUE READING
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