Mechanisms of Antiaddictive Actions of Ibogaine a

@article{Glick1998MechanismsOA,
  title={Mechanisms of Antiaddictive Actions of Ibogaine a},
  author={S. Glick and I. M. Maisonneuve},
  journal={Annals of the New York Academy of Sciences},
  year={1998},
  volume={844}
}
  • S. Glick, I. M. Maisonneuve
  • Published 1998
  • Chemistry, Medicine
  • Annals of the New York Academy of Sciences
  • ABSTRACT: Ibogaine, an alkaloid extracted from Tabemanthe iboga, is being studied as a potential long‐acting treatment for oploid and stimulant abuse as well as for alcoholism and smoking. Studies in this laboratory have used animal models to characterize ibogaine's interactions with drugs of abuse, and to investigate the mechanisms responsible. Ibogaine, as well as its metabolite, noribogaine, can decrease both morphine and cocaine self‐administration for several days in some rats; shorter… CONTINUE READING
    73 Citations
    Application of Electrophysiological Method to Study Interactions between Ibogaine and Cocaine
    • 5
    Iboga interactions with psychomotor stimulants: panacea in the paradox?
    • 10
    Noribogaine (12‐Hydroxyibogamine): A Biologically Active Metabolite of the Antiaddictive Drug Ibogaine
    • 27
    In vivo neurobiological effects of ibogaine and its O-desmethyl metabolite, 12-hydroxyibogamine (noribogaine), in rats.
    • 50
    • Highly Influenced
    • PDF
    Long-Lasting Ibogaine Protection against NMDA-Induced Convulsions in Mice
    • 22

    References

    SHOWING 1-10 OF 32 REFERENCES
    Ibogaine-like effects of noribogaine in rats
    • 65
    • PDF
    NMDA antagonist properties of the putative antiaddictive drug, ibogaine.
    • 96
    Ibogaine neurotoxicity: a re-evaluation
    • 58
    • PDF