Mechanisms of Age-Related Macular Degeneration

  title={Mechanisms of Age-Related Macular Degeneration},
  author={Jayakrishna Ambati and Benjamin J. Fowler},
Age-related macular degeneration (AMD), a progressive condition that is untreatable in up to 90% of patients, is a leading cause of blindness in the elderly worldwide. The two forms of AMD, wet and dry, are classified based on the presence or absence of blood vessels that have disruptively invaded the retina, respectively. A detailed understanding of the molecular mechanisms underlying wet AMD has led to several robust FDA-approved therapies. In contrast, there are no approved treatments for… CONTINUE READING
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