Mechanisms of β-lactam antimicrobial resistance and epidemiology of major community- and healthcare-associated multidrug-resistant bacteria.

@article{Tang2014MechanismsO,
  title={Mechanisms of β-lactam antimicrobial resistance and epidemiology of major community- and healthcare-associated multidrug-resistant bacteria.},
  author={Sarah Si Lin Tang and Anucha Apisarnthanarak and Li Yang Hsu},
  journal={Advanced drug delivery reviews},
  year={2014},
  volume={78},
  pages={
          3-13
        }
}
Alexander Fleming's discovery of penicillin heralded an age of antibiotic development and healthcare advances that are premised on the ability to prevent and treat bacterial infections both safely and effectively. The resultant evolution of antimicrobial resistant mechanisms and spread of bacteria bearing these genetic determinants of resistance are acknowledged to be one of the major public health challenges globally, and threatens to unravel the gains of the past decades. We describe the… CONTINUE READING
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