Mechanisms maintaining the dormancy and survival of mammalian primordial follicles.

@article{Reddy2010MechanismsMT,
  title={Mechanisms maintaining the dormancy and survival of mammalian primordial follicles.},
  author={P. Vamshi Krishna Reddy and Wenjing Zheng and Kui Kui Liu},
  journal={Trends in endocrinology and metabolism: TEM},
  year={2010},
  volume={21 2},
  pages={96-103}
}
To preserve the length of a woman's reproductive life it is essential that the majority of her ovarian primordial follicles are maintained in a quiescent state to provide a reserve for continuous reproductive success. The mechanisms maintaining the dormancy and survival of primordial follicles have been a mystery for decades. In recent years information provided by genetically modified mouse models has revealed a number of molecules whose functions are indispensable for the maintenance of… CONTINUE READING

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