Mechanisms involved in vitamin E transport by primary enterocytes and in vivo absorption.

  title={Mechanisms involved in vitamin E transport by primary enterocytes and in vivo absorption.},
  author={Kamran Anwar and Jahangir Iqbal and M. Mahmood Hussain},
  journal={Journal of lipid research},
  volume={48 9},
It is generally believed that vitamin E is absorbed along with chylomicrons. However, we previously reported that human colon carcinoma Caco-2 cells use dual pathways, apolipoprotein B (apoB)-lipoproteins and HDLs, to transport vitamin E. Here, we used primary enterocytes and rodents to identify in vivo vitamin E absorption pathways. Uptake of [(3)H]alpha-tocopherol by primary rat and mouse enterocytes increased with time and reached a maximum at 1 h. In the absence of exogenous lipid supply… CONTINUE READING


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