Mechanisms for the anti-inflammatory effects of adiponectin in macrophages.

@article{Huang2008MechanismsFT,
  title={Mechanisms for the anti-inflammatory effects of adiponectin in macrophages.},
  author={Honglian Huang and Pil-Hoon Park and Megan R. McMullen and Laura E Nagy},
  journal={Journal of gastroenterology and hepatology},
  year={2008},
  volume={23 Suppl 1},
  pages={
          S50-3
        }
}
Adiponectin is an adipokine with potent anti-inflammatory properties. The development of alcoholic liver disease is thought to involve increased pro-inflammatory activity, mediated in part by the activation of hepatic macrophages (Kupffer cells). Chronic ethanol feeding sensitizes hepatic macrophages to activation by lipopolysaccharide (LPS), leading to increased production of reactive oxygen species and tumor necrosis factor-alpha (TNF-alpha). Adiponectin can normalize Toll-like receptor-4… CONTINUE READING

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Adiponectin and its Hydrolase-Activated Receptors.

  • Journal of nature and science
  • 2017
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