Mechanisms for differential block among single myelinated and non-myelinated axons by procaine.

@article{Franz1974MechanismsFD,
  title={Mechanisms for differential block among single myelinated and non-myelinated axons by procaine.},
  author={D. S. Feingold N. Findlay G. Franz and Raymond S. Perry},
  journal={The Journal of physiology},
  year={1974},
  volume={236 1},
  pages={193-210}
}
1. The differential sensitivity of saphenous nerve fibres in the cat to block by procaine HCl was re-examined by recording identifiable unit action potentials from small nerve filaments.2. Small myelinated axons were blocked more quickly than large myelinated axons, but this differential effect could not be accounted for by differences in anaesthetic concentration requirements.3. The onset of block in non-myelinated axons was slower than or equal to that of small myelinated axons depending on… CONTINUE READING

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