Mechanisms for bacterial gliding motility on soft substrates

  title={Mechanisms for bacterial gliding motility on soft substrates},
  author={Jo{\"e}l Tchoufag and Pushpita Ghosh and Connor B. Pogue and Beiyan Nan and Kranthi K. Mandadapu},
  journal={Proceedings of the National Academy of Sciences},
  pages={25087 - 25096}
Significance Gliding motility is the ability of certain rod-shaped bacteria to translocate on surfaces without the aid of external appendages such as flagella, cilia, or pili. This motility is crucial to their developmental cycle because it regulates their proliferation in the presence of nutrients or aggregation to form fruiting bodies in starvation conditions. Using myxobacteria as a canonical example of these organisms, we show that single-cell gliding is mediated by elastic, viscous, and… 

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Bacterial gliding motility: multiple mechanisms for cell movement over surfaces.

  • M. McBride
  • Biology
    Annual review of microbiology
  • 2001
Genetic, biochemical, ultrastructural, and behavioral studies are providing insight into the machineries employed by these diverse bacteria that enable them to glide over surfaces.

Novel mechanisms power bacterial gliding motility

Recent findings made on the gliding mechanisms of the myxobacteria, flavobacteria and mycoplasmas are summarized to provide rich source materials for studying the function and evolution of complex microbial nanomachines.

Uncovering the mystery of gliding motility in the myxobacteria.

Recent studies suggest that gliding motility in M. xanthus involves large multiprotein structural complexes, regulatory proteins, and cytoskeletal filaments, and alternative models for gliding are discussed.

Myxobacteria gliding motility requires cytoskeleton rotation powered by proton motive force

Evidence is presented that periplasmic AgmU decorates a looped continuous helix that rotates clockwise as cells glide forward, reversing its rotation when cells reverse polarity, which is consistent with a mechanochemical model in which PMF-driven motors run along an endless looped helical track.

MotAB-like machinery drives the movement of MreB filaments during bacterial gliding motility

It is found that a subpopulation of MreB particles moves rapidly along helical trajectories, similar to the movements of the MotAB-like gliding motors, and this rapid movement was not affected by the inhibitors of cell wall biosynthesis.

Flagella stator homologs function as motors for myxobacterial gliding motility by moving in helical trajectories

This work shows that the untethered gliding motors of M. xanthus, by moving within the membrane, can transform helical motion into linear driving forces that push against the surface.

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