Mechanisms employed by herpes simplex virus 1 to inhibit the interferon response.

@article{Paladino2009MechanismsEB,
  title={Mechanisms employed by herpes simplex virus 1 to inhibit the interferon response.},
  author={Patrick Paladino and Karen Louise Mossman},
  journal={Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research},
  year={2009},
  volume={29 9},
  pages={599-607}
}
The interferon (IFN) family of cytokines constitutes potent inducers of innate antiviral responses that also influence adaptive immune processes. Despite eliciting such formidable cellular defense responses, viruses have evolved ways to interfere with the IFN response. Herpes simplex virus 1 (HSV-1) is an enveloped, dsDNA virus and a member of the herpesvirus family. Like other herpesvirus family members, HSV-1 has become highly specialized for its host and establishes a lifelong infection by… CONTINUE READING

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