Mechanisms controlling normal defecation and the potential effects of spinal cord injury.

@article{Brading2006MechanismsCN,
  title={Mechanisms controlling normal defecation and the potential effects of spinal cord injury.},
  author={Alison Frances Brading and Thanesan Ramalingam},
  journal={Progress in brain research},
  year={2006},
  volume={152},
  pages={345-58}
}
Spinal cord injury frequently leads to bowel dysfunction with the result that emptying the bowel can occupy a significant part of the day and reduce the quality of life. This chapter contains an overview of the function and morphology of the normal distal gut in the human, and of gut behaviour in normal defecation. In humans, this can be monitored and is described, but knowledge of the mechanisms controlling it is limited. Work on animals has shown that the intrinsic activity of the smooth… CONTINUE READING