Mechanisms controlling germline cyst breakdown and primordial follicle formation

Abstract

In fetal females, oogonia proliferate immediately after sex determination. The progress of mitosis in oogonia proceeds so rapidly that the incompletely divided cytoplasm of the sister cells forms cysts. The oogonia will then initiate meiosis and arrest at the diplotene stage of meiosis I, becoming oocytes. Within each germline cyst, oocytes with Balbiani… (More)
DOI: 10.1007/s00018-017-2480-6

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