Mechanisms controlling axonal sprouting at the neuromuscular junction.

@article{Tam2003MechanismsCA,
  title={Mechanisms controlling axonal sprouting at the neuromuscular junction.},
  author={Siu Lin Tam and Tessa Gordon},
  journal={Journal of neurocytology},
  year={2003},
  volume={32 5-8},
  pages={961-74}
}
This review considers the relative roles of sprouting stimuli, perisynaptic Schwann cells and neuromuscular activity in axonal sprouting at the neuromuscular junction in partially denervated muscles. A number of sprouting stimuli, including insulin-like growth factor II, which are generated from inactive muscle fibers in partially denervated and paralyzed skeletal muscles, has been considered. There is also evidence that perisynaptic Schwann cells induce and guide axonal sprouting in adult… CONTINUE READING

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