Mechanisms controlling arrangements and movements of nuclei in pseudostratified epithelia.

  title={Mechanisms controlling arrangements and movements of nuclei in pseudostratified epithelia.},
  author={Hyun O. Lee and Caren Norden},
  journal={Trends in cell biology},
  volume={23 3},
During development, cells undergo complex rearrangements that contribute to the final tissue architecture. A characteristic arrangement found in rapidly expanding, highly proliferative tissues is pseudostratified epithelium, which features notably elongated cells with varied nuclear positions along the cell axis. Although anomalies in its structure are implicated in diseases like microcephaly, how pseudostratification is formed and maintained remains elusive. In this review, we focus on a… CONTINUE READING
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