Mechanisms contributing to central excitability changes during hearing loss.

@article{Pilati2012MechanismsCT,
  title={Mechanisms contributing to central excitability changes during hearing loss.},
  author={Nadia Pilati and Matias J. Ison and Matthew Barker and Mike Mulheran and Charles H. Large and Ian D. Forsythe and John Matthias and Martine Hamann},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2012},
  volume={109 21},
  pages={8292-7}
}
Exposure to loud sound causes cochlear damage resulting in hearing loss and tinnitus. Tinnitus has been related to hyperactivity in the central auditory pathway occurring weeks after loud sound exposure. However, central excitability changes concomitant to hearing loss and preceding those periods of hyperactivity, remain poorly explored. Here we investigate mechanisms contributing to excitability changes in the dorsal cochlear nucleus (DCN) shortly after exposure to loud sound that produces… CONTINUE READING
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