Mechanisms by which cAMP increases bile acid secretion in rat liver and canalicular membrane vesicles.

@article{Misra2003MechanismsBW,
  title={Mechanisms by which cAMP increases bile acid secretion in rat liver and canalicular membrane vesicles.},
  author={Suniti Misra and Lyuba Varticovski and Irwin M. Arias},
  journal={American journal of physiology. Gastrointestinal and liver physiology},
  year={2003},
  volume={285 2},
  pages={G316-24}
}
Bile acid secretion induced by cAMP and taurocholate is associated with recruitment of several ATP binding cassette (ABC) transporters to the canalicular membrane. Taurocholate-mediated bile acid secretion and recruitment of ABC transporters are phosphatidylinositol 3-kinase (PI3K) dependent and require an intact microtubular apparatus. We examined… CONTINUE READING