Mechanisms behind the anti-inflammatory actions of insulin.

  title={Mechanisms behind the anti-inflammatory actions of insulin.},
  author={Eric D. Hyun and Rithwik Ramachandran and Morley D Hollenberg and Nathalie Vergnolle},
  journal={Critical reviews in immunology},
  volume={31 4},
The epidemic of diabetes mellitus is worsening worldwide. Diabetes mellitus is a chronic metabolic disease characterized by inappropriate recurrent or persistent hyperglycemia. Numerous studies have demonstrated that hyperglycemia, the most significant predictor of poor clinical outcome in diabetes mellitus patients, can directly promote an inflammatory response and oxidative stress. Although there are various causes of DM, all eventually lead to absolute or relative insulin deficiency and… CONTINUE READING
Highly Cited
This paper has 34 citations. REVIEW CITATIONS


Publications citing this paper.
Showing 1-10 of 20 extracted citations