Mechanisms behind changes in gastric acid and bicarbonate outputs during the human interdigestive motility cycle.

@article{Dalenbck1996MechanismsBC,
  title={Mechanisms behind changes in gastric acid and bicarbonate outputs during the human interdigestive motility cycle.},
  author={Jan Dalenb{\"a}ck and Lars F{\"a}ndriks and Lars Olbe and Henrik Sj{\"o}vall},
  journal={The American journal of physiology},
  year={1996},
  volume={270 1 Pt 1},
  pages={
          G113-22
        }
}
Human gastric interdigestive acid and bicarbonate outputs vary cyclically in association with the migrating motor complex (MMC). These phenomena were studied in 26 healthy volunteers by constant-flow gastric perfusion, with continuous recording of pH and Pco2 in mixed gastric effluent and concomitant open-tip manometry of gastroduodenal motility. Stable acid and bicarbonate outputs were registered during less than 50% of the MMC cycle. Acid secretion started to increase 71 +/- 3% into the cycle… CONTINUE READING

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