Mechanisms and treatment of allergic disease in the big picture of regulatory T cells.

@article{Akdis2009MechanismsAT,
  title={Mechanisms and treatment of allergic disease in the big picture of regulatory T cells.},
  author={Cezmi A. Akdis and M{\"u}beccel Akdis},
  journal={The Journal of allergy and clinical immunology},
  year={2009},
  volume={123 4},
  pages={735-46; quiz 747-8}
}
Various populations of regulatory T (Treg) cells have been shown to play a central role in the maintenance of peripheral homeostasis and the establishment of controlled immune responses. Their identification as key regulators of immunologic processes in peripheral tolerance to allergens has opened an important era in the prevention and treatment of allergic diseases. Both naturally occurring CD4+CD25+ Treg cells and inducible populations of allergen-specific, IL-10-secreting Treg type 1 (T(R)1… CONTINUE READING

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