Mechanisms and role of microRNA deregulation in cancer onset and progression

  title={Mechanisms and role of microRNA deregulation in cancer onset and progression},
  author={Edenir In{\^e}s Palmero and Silvana Gisele Pegorin de Campos and Marcelo M Vallette Campos and Naiara Correia Nogueira de Souza and Ismael Dale Coltrin Guerreiro and Andr{\'e} Lopes Carvalho and M{\'a}rcia Maria Chiquitelli Marques},
  booktitle={Genetics and molecular biology},
MicroRNAs are key regulators of various fundamental biological processes and, although representing only a small portion of the genome, they regulate a much larger population of target genes. Mature microRNAs (miRNAs) are single-stranded RNA molecules of 20-23 nucleotide (nt) length that control gene expression in many cellular processes. These molecules typically reduce the stability of mRNAs, including those of genes that mediate processes in tumorigenesis, such as inflammation, cell cycle… CONTINUE READING
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