Mechanisms and mediators of nasal symptoms in non-allergic rhinitis.

@article{Salib2008MechanismsAM,
  title={Mechanisms and mediators of nasal symptoms in non-allergic rhinitis.},
  author={Rami J. Salib and Philip G. Harries and S B Nair and Peter Howarth},
  journal={Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology},
  year={2008},
  volume={38 3},
  pages={
          393-404
        }
}
Non-allergic rhinitis may be a contributing factor in up to 60% of rhinitis patients and a sole contributor in a quarter. It is a highly heterogeneous condition with poorly understood pathophysiological mechanisms. Compelling evidence is emerging of a localized nasal mucosal allergic response in some non-allergic rhinitic subjects in the absence of systemic atopy. While the inflammatory disease pathway in non-allergic rhinitis may share some of the features of its allergic counterpart, overall… CONTINUE READING

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