Mechanisms and Significance of Cell Volume Regulation

@article{Lang2007MechanismsAS,
  title={Mechanisms and Significance of Cell Volume Regulation},
  author={F. Lang},
  journal={Journal of the American College of Nutrition},
  year={2007},
  volume={26},
  pages={613S - 623S}
}
  • F. Lang
  • Published 2007
  • Chemistry, Medicine
  • Journal of the American College of Nutrition
  • Survival of human and animal cells requires avoidance of excessive alterations of cell volume. The osmolarity amassed by cellular accumulation of organic substances must be compensated by lowering cytosolic ion concentrations. The Na+/K+ ATPase extrudes Na+ in exchange for K+, which can permeate the cell membrane through K+ channels. K+ exit generates a cell-negative potential difference across the cell membrane, driving the exit of anions such as Cl−. The low cytosolic Cl− concentrations… CONTINUE READING
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    References

    SHOWING 1-10 OF 82 REFERENCES
    The Diversity of Volume Regulatory Mechanisms
    • 299
    Membrane mechanisms and intracellular signalling in cell volume regulation.
    • 475
    • Highly Influential
    Ion Channels in Cell Proliferation and Apoptotic Cell Death
    • 290
    • PDF
    Functional significance of cell volume regulatory mechanisms.
    • 1,724
    • PDF
    Regulation of the Cellular Content of the Organic Osmolyte Taurine in Mammalian Cells
    • I. Lambert
    • Biology, Medicine
    • Neurochemical Research
    • 2004
    • 171
    Mechanisms Sensing and Modulating Signals Arising From Cell Swelling
    • 129
    Sensors and signal transduction pathways in vertebrate cell volume regulation.
    • 54
    Cell volume-sensitive chloride channels: phenotypic properties and molecular identity.
    • Y. Okada
    • Biology, Medicine
    • Contributions to nephrology
    • 2006
    • 69
    Cell volume homeostasis: ionic and nonionic mechanisms. The sodium pump in the emergence of animal cells.
    • W. Stein
    • Biology, Chemistry
    • International review of cytology
    • 2002
    • 36
    Calcium signaling in cell volume regulation.
    • 337