Mechanisms and Dynamics of Cortical Motor Inhibition in the Stop-signal Paradigm: A TMS Study

@article{Wildenberg2010MechanismsAD,
  title={Mechanisms and Dynamics of Cortical Motor Inhibition in the Stop-signal Paradigm: A TMS Study},
  author={Wery P. M. van den Wildenberg and Bor{\'i}s Burle and Franck Vidal and Maurits W. van der Molen and K. Richard Ridderinkhof and Thierry Hasbroucq},
  journal={Journal of Cognitive Neuroscience},
  year={2010},
  volume={22},
  pages={225-239}
}
The ability to stop ongoing motor responses in a split-second is a vital element of human cognitive control and flexibility that relies in large part on prefrontal cortex. We used the stop-signal paradigm to elucidate the engagement of primary motor cortex (M1) in inhibiting an ongoing voluntary motor response. The stop-signal paradigm taps the ability to flexibly countermand ongoing voluntary behavior upon presentation of a stop signal. We applied single-pulse TMS to M1 at several intervals… CONTINUE READING
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