Mechanisms Behind the Inhibition of Lung Adenocarcinoma Cell by Shikonin

@inproceedings{Lan2014MechanismsBT,
  title={Mechanisms Behind the Inhibition of Lung Adenocarcinoma Cell by Shikonin},
  author={Wenjing Lan and Shengbang Wan and Weiqing Gu and Heyong Wang and Songwen Zhou},
  booktitle={Cell Biochemistry and Biophysics},
  year={2014}
}
Shikonin, a natural naphthoquinone isolated from a traditional Chinese medicinal herb, can exert inhibitory effect on tumor cell growth. However, little has been known concerning the effect of shikonin on lung adenocarcinoma cell and underlying mechanisms. In the present study, we investigated the effect of shikonin on the proliferation, cell cycle arrest, and apoptosis in human lung adenocarcinoma cells. We found that shikonin significantly suppressed the proliferation of lung adenocarcinoma… CONTINUE READING
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