Mechanisms, regulation and pathologic significance of Mg2+ efflux from erythrocytes.

@article{Gnther2006MechanismsRA,
  title={Mechanisms, regulation and pathologic significance of Mg2+ efflux from erythrocytes.},
  author={Theodor G{\"u}nther},
  journal={Magnesium research},
  year={2006},
  volume={19 3},
  pages={190-8}
}
Mg2+ efflux from erythrocytes can be performed by the Na+/Mg2+ antiport and by Na+-independent Mg2+ efflux. Na+-independent Mg2+ efflux functions via the unspecific choline exchanger as choline/Mg2+ or K+/Mg2+ antiport and as Mg2+ efflux accompanied by intracellular Cl- for charge compensation, as found for example in sucrose medium. Na+/Mg2+ antiport in erythrocytes exchanges 2 extracellular Na+ for 1 intracellular Mg2+. Driving forces are the Na+ and Mg2+ gradients. By reversing these… CONTINUE READING