Mechanism of the myelin basic protein-induced insulin and glucagon release from isolated rat pancreatic islets.

The central nervous system myelin basic protein (MBP) stimulates the release of several peptide hormones including insulin and glucagon. This could be associated with the development of hyperglycaemia in neurological disorders such as stroke, in which MBP is known to leak into blood circulation. In the present study the mechanism of insulin and glucagon… CONTINUE READING