Mechanism of the antibiotic action pyocyanine.

@article{Hassan1980MechanismOT,
  title={Mechanism of the antibiotic action pyocyanine.},
  author={H. Moustafa Hassan and Irwin Fridovich},
  journal={Journal of bacteriology},
  year={1980},
  volume={141 1},
  pages={
          156-63
        }
}
Exposure of Escherichia coli growing in a rich medium to pyocyanine resulted in increased intracellular levels of superoxide dismutase and of catalase. When these adaptive enzyme syntheses were prevented by nutritional paucity, the toxic action of pyocyanine was augmented. The antibiotic action of pyocyanine was dependent upon oxygen and was diminished by superoxide dismutase and by catalase, added to the suspending medium. Pyocyanine slightly augmented the respiration of E. coli suspended in a… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 123 CITATIONS, ESTIMATED 66% COVERAGE

The Pseudomonas secretory product pyocyanin inhibits catalase activity in human lung epithelial cells.

  • American journal of physiology. Lung cellular and molecular physiology
  • 2003
VIEW 16 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Subcellular localization of Pseudomonas pyocyanin cytotoxicity in human lung epithelial cells.

  • American journal of physiology. Lung cellular and molecular physiology
  • 2003
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Molecular mechanism of the antimicrobial action of pyocyanin

VIEW 8 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Pseudomonas aeruginosa in premise plumbing of large buildings

VIEW 3 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

1983
2019

CITATION STATISTICS

  • 18 Highly Influenced Citations