Mechanism of resistance to sulphite in Saccharomyces cerevisiae

  title={Mechanism of resistance to sulphite in Saccharomyces cerevisiae},
  author={Enrico Casalone and Carlo M. Colella and Simona Daly and Enzo Gallori and Luca Moriani and Mario Polsinelli},
  journal={Current Genetics},
Growth inhibition and cell killing caused by sulphite were reduced in seven Saccharomyces cerevisiae sulphite-resistant independent mutants, compared to their parental strains. Genetic analysis showed that in the seven mutants resistance was inherited as a single-gene dominant mutation and that all the analyzed mutations were allelic, thus identifying a major gene responsible for sulphite resistance in S. cerevisiae. Two of the mutants, MBS20-9 and MBS30, were further characterized. 35S… CONTINUE READING