Mechanism of radioprotection by δ-tocotrienol: pharmacokinetics, pharmacodynamics and modulation of signalling pathways.

Abstract

OBJECTIVE The objective of this study was to investigate the correlation between in vivo δ-tocotrienol (DT3) pharmacokinetics, pharmacodynamics and radiation protection, and to evaluate the effect of DT3 pre-treatment on radiation-induced alterations in apoptotic and autophagic pathways. METHODS We evaluated pharmacokinetics (plasma, 0.5 to 12 h) and… (More)
DOI: 10.1259/bjr/63355844

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@article{Satyamitra2012MechanismOR, title={Mechanism of radioprotection by δ-tocotrienol: pharmacokinetics, pharmacodynamics and modulation of signalling pathways.}, author={Merriline M Satyamitra and Philip Ney and J. P. Graves and Colin Mullaney and Vidhya Srinivasan}, journal={The British journal of radiology}, year={2012}, volume={85 1019}, pages={e1093-103} }