Mechanism of osteoporosis in adolescent idiopathic scoliosis: experimental scoliosis in pinealectomized chickens.

@article{Kono2011MechanismOO,
  title={Mechanism of osteoporosis in adolescent idiopathic scoliosis: experimental scoliosis in pinealectomized chickens.},
  author={Hitoshi Kono and Masafumi Machida and Masashi Saito and Yuji Nishiwaki and H. Ogata H. Kato and Naobumi Hosogane and Kazuhiro Chiba and Takeshi Miyamoto and Morio Matsumoto and Yoshiaki Toyama},
  journal={Journal of pineal research},
  year={2011},
  volume={51 4},
  pages={387-93}
}
To clarify the mechanism of osteoporosis in adolescent idiopathic scoliosis (AIS), we investigated radiological and histological changes in the cervical vertebrae of a chicken thoracic scoliosis model. Forty newly hatched broiler chicks were randomly divided into four equal groups: sham-operated chickens serving as control (CON), pinealectomized chickens (PNX), sham-operated (CON + MLT) and pinealectomized chickens (PNX + MLT) that received intraperitoneal administration of melatonin… CONTINUE READING
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