Mechanism of opioid-induced pupillary effects

@article{Larson2008MechanismOO,
  title={Mechanism of opioid-induced pupillary effects},
  author={M. Larson},
  journal={Clinical Neurophysiology},
  year={2008},
  volume={119},
  pages={1358-1364}
}
  • M. Larson
  • Published 2008
  • Psychology, Medicine
  • Clinical Neurophysiology
OBJECTIVE This study tested the hypothesis that increased activity in the pupilloconstrictor nucleus by the addition of ambient light and by the administration of fentanyl, sufficient to block pupillary reflex dilation, constricts the pupil of anesthetized patients. METHODS Pupil diameter was measured in 10 anesthetized patients during noxious stimulation above an epidural block level, in darkness and then with light directed into the left eye. Two measurements were taken from the right eye… Expand
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