Mechanism of myocardial microvessel formation in cyanotic congenital heart disease.

@article{Hu2005MechanismOM,
  title={Mechanism of myocardial microvessel formation in cyanotic congenital heart disease.},
  author={Jiaxin Hu and Peiwu Sun and Xinmin Ruan and Aiqing Chao and Yu Yung Lin and Xiang Yu Li},
  journal={Circulation journal : official journal of the Japanese Circulation Society},
  year={2005},
  volume={69 9},
  pages={
          1089-93
        }
}
BACKGROUND Patients with cyanotic congenital heart disease (C-CHD) usually have myocardial thickening and fibrosis, both of which can affect the course of surgical management. Hypoxia and ischemia may stimulate microvessel formation in the myocardium, which may accelerate the myocardial thickening and fibrosis. Whether hyperplasia of microvessels occurs in the myocardium of C-CHD was investigated in this report. METHODS AND RESULTS The patients were divided into 2 groups; the C-CHD group (n… CONTINUE READING

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