Mechanism of mineral formation in bone.

@article{Anderson1989MechanismOM,
  title={Mechanism of mineral formation in bone.},
  author={Harrison C Anderson},
  journal={Laboratory investigation; a journal of technical methods and pathology},
  year={1989},
  volume={60 3},
  pages={320-30}
}
The mechanism of mineral formation in bone is seen best where active new bone formation is occurring, e.g., in newly forming subperiosteal bone of the embryo, in the growing bone of young animals, and in healing rickets where the calcification process in osteoid is reactivated. A large body of ultrastructural evidence, using conventional and anhydrous methods for tissue preparation, has shown convincingly that extracellular matrix vesicles are present at or near the mineralization front in all… CONTINUE READING

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