Mechanism of membrane damage mediated by human eosinophil cationic protein

@article{Young1986MechanismOM,
  title={Mechanism of membrane damage mediated by human eosinophil cationic protein},
  author={J. Young and C. Peterson and P. Venge and Z. Cohn},
  journal={Nature},
  year={1986},
  volume={321},
  pages={613-616}
}
Recent evidence suggests a role for eosinophil granule proteins in contact-dependent antibody-mediated cytotoxicity1–3. Cytolysis may involve a secretory phenomenon whereby granule proteins are released at the site of contact between eosinophil and target cells1–4. Several basic proteins have been isolated from eosinophil granules, including the major basic protein5–7, eosinophil cationic protein8,9, eosinophil protein-X10 and eosinophil peroxidase11. One of the major granule proteins of human… Expand
Eosinophil Cationic Protein ( ECP ) Is Processed during Secretion 1
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