Mechanism of localization of 99mTc-labeled pyrophosphate and tetracycline in infarcted myocardium.

@article{Dewanjee1976MechanismOL,
  title={Mechanism of localization of 99mTc-labeled pyrophosphate and tetracycline in infarcted myocardium.},
  author={Mrinal K. Dewanjee and Peter C. Kahn},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year={1976},
  volume={17 7},
  pages={639-46}
}
The gross and subcellular localizations of 99mTc-labeled pyrophosphate and tetracycline in myocardial infarcts were studied in a rabbit model. Experiments utilizing double-nuclide labeling were carried out using a useful mapping technique. Concentration of the various chelates decreases in an expected manner from the center of the infarcted area toward its periphery, but it is higher near the epicardial surface than toward the endocardium. Technetium-99m-pyrophosphate is concentrated in the… CONTINUE READING