Mechanism of intranasal drug delivery directly to the brain

  title={Mechanism of intranasal drug delivery directly to the brain},
  author={Tyler P. Crowe and H. Greenlee and A. Kanthasamy and W. Hsu},
  journal={Life Sciences},
  • Tyler P. Crowe, H. Greenlee, +1 author W. Hsu
  • Published 2018
  • Medicine
  • Life Sciences
  • &NA; Neurological diseases are becoming increasingly prominent worldwide due to rapidly aging populations, which greatly contributes to increasing healthcare costs. The development of neuroprotective drugs has so far proven exceptionally difficult due to the blood‐brain barrier. One novel approach to address this challenge is to administer drugs intranasally to noninvasively bypass the blood‐brain barrier. The intranasal route can thus transport drugs directly to the brain from the nasal cavity… CONTINUE READING
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