Mechanism of intranasal drug delivery directly to the brain

@article{Crowe2018MechanismOI,
  title={Mechanism of intranasal drug delivery directly to the brain},
  author={Tyler P. Crowe and Heather West Greenlee and Anumantha G. Kanthasamy and Walter H Hsu},
  journal={Life Sciences},
  year={2018},
  volume={195},
  pages={44–52}
}
&NA; Neurological diseases are becoming increasingly prominent worldwide due to rapidly aging populations, which greatly contributes to increasing healthcare costs. The development of neuroprotective drugs has so far proven exceptionally difficult due to the blood‐brain barrier. One novel approach to address this challenge is to administer drugs intranasally to noninvasively bypass the blood‐brain barrier. The intranasal route can thus transport drugs directly to the brain from the nasal cavity… 
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