Mechanism of hydroxylamine-induced inhibition of beta-galactosidase synthesis in Escherichia coli.

@article{Basu1967MechanismOH,
  title={Mechanism of hydroxylamine-induced inhibition of beta-galactosidase synthesis in Escherichia coli.},
  author={S. K. Basu and A. Chakrabarty and S. Roy},
  journal={Biochemical and biophysical research communications},
  year={1967},
  volume={29 4},
  pages={
          463-8
        }
}
Abstract Kepes and Beguin (1966) demonstrated an inhibition of induced β-galatosidase peptide synthesis by hydroxylamine (HA) without effect on messenger RNA (m-RNA) formation. The mechanism by which HA inhibits chain initiation is unclear, as is the question whether the effect is general or only specific for the β-galactosidase peptide. Experiments with E. coli strains K12 (λ) and 113-3 (a met, B12 auxotroph, Davis and Mingioli, 1950 ) indicated more severe inhibition of β-galactosidase… Expand
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