Mechanism of higher oxygen consumption rate: pressure-loaded vs. volume-loaded heart.

@article{Suga1982MechanismOH,
  title={Mechanism of higher oxygen consumption rate: pressure-loaded vs. volume-loaded heart.},
  author={Hiroyuki Suga and R Hisano and Shinichi Hirata and Taiji Hayashi and Ishio Ninomiya},
  journal={The American journal of physiology},
  year={1982},
  volume={242 6},
  pages={H942-8}
}
The greater cardiac oxygen consumption (VO2) under pressure than under volume load has been accounted for by the greater ventricular wall force under pressure load. We cannot fully agree with this because the wall force has not always been uniquely correlated with VO2. We attempted to account for the greater VO2 under pressure load by the ventricular systolic pressure-volume area (PVA), which we previously showed uniquely correlated with VO2. In isolated supported canine hearts, we produced… CONTINUE READING

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