Mechanism of genome transcription in segmented dsRNA viruses.

@article{Lawton2000MechanismOG,
  title={Mechanism of genome transcription in segmented dsRNA viruses.},
  author={Jeffrey A. Lawton and Mary K. Estes and B. V. Venkataram Prasad},
  journal={Advances in virus research},
  year={2000},
  volume={55},
  pages={185-229}
}
Genome transcription is a critical stage in the life cycle of a virus, as this is the process by which the viral genetic information is presented to the host cell protein synthesis machinery for the production of the viral proteins needed for genome replication and progeny virion assembly. Viruses with dsRNA genomes face a particular challenge in that host cells do not produce proteins which can transcribe from a dsRNA template. Therefore, dsRNA viruses contain all of the necessary enzymatic… CONTINUE READING

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