Mechanism of extracellular ubiquitination in the mammalian epididymis.

@article{Baska2008MechanismOE,
  title={Mechanism of extracellular ubiquitination in the mammalian epididymis.},
  author={Kathleen M. Baska and Gaurishankar Manandhar and Dawn Feng and Yuksel Agca and Mark W. Tengowski and Miriam Sutovsky and Y. J. Yi and Peter Sutovsky},
  journal={Journal of cellular physiology},
  year={2008},
  volume={215 3},
  pages={
          684-96
        }
}
Posttranslational modification by ubiquitination marks defective or outlived intracellular proteins for proteolytic degradation by the 26S proteasome. The ATP-dependent, covalent ligation and formation of polyubiquitin chains on substrate proteins requires the presence and activity of a set of ubiquitin activating and conjugating enzymes. While protein ubiquitination typically occurs in the cell cytosol or nucleus, defective mammalian spermatozoa become ubiquitinated on their surface during… CONTINUE READING
Highly Cited
This paper has 38 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 16 citations