Mechanism of concentration-dependent induction of heme oxygenase-1 by resveratrol in human aortic smooth muscle cells.

@article{Juan2005MechanismOC,
  title={Mechanism of concentration-dependent induction of heme oxygenase-1 by resveratrol in human aortic smooth muscle cells.},
  author={Soong Cai Juan and Tzu-Hurng Cheng and Hui‐Chen Lin and Yong Song Chu and Wen-Sen Lee},
  journal={Biochemical pharmacology},
  year={2005},
  volume={69 1},
  pages={
          41-8
        }
}
Resveratrol-mediated heme oxygenase-1 (HO-1) induction has been shown to occur in primary neuronal cultures and is thought to have potential neuroprotective action. Further, antioxidant properties of resveratrol have been reported to protect against coronary heart disease. We attempted to examine resveratrol's HO-1 inducing potency and its induction regulation in human aortic smooth muscle cells (HASMC). We showed that resveratrol-mediated HO-1 induction occurred in concentration- and time… CONTINUE READING
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