Mechanism of biological denitrification inhibition: procyanidins induce an allosteric transition of the membrane-bound nitrate reductase through membrane alteration.

@article{Bardon2016MechanismOB,
  title={Mechanism of biological denitrification inhibition: procyanidins induce an allosteric transition of the membrane-bound nitrate reductase through membrane alteration.},
  author={Clément Bardon and Franck Poly and Florence Piola and Muriel Pancton and Gilles Comte and Guillaume Meiffren and Feth El Zahar Haichar},
  journal={FEMS microbiology ecology},
  year={2016},
  volume={92 5},
  pages={
          fiw034
        }
}
Recently, it has been shown that procyanidins from Fallopia spp. inhibit bacterial denitrification, a phenomenon called biological denitrification inhibition (BDI). However, the mechanisms involved in such a process remain unknown. Here, we investigate the mechanisms of BDI involving procyanidins, using the model strain Pseudomonas brassicacearum NFM 421. The aerobic and anaerobic (denitrification) respiration, cell permeability and cell viability of P. brassicacearum were determined as a… CONTINUE READING
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