Mechanism of antimutagenicity of wheat sprout extracts.

  title={Mechanism of antimutagenicity of wheat sprout extracts.},
  author={B Peryt and Teresa Szymczyk and P Lesca},
  journal={Mutation research},
  volume={269 2},
In this paper we have demonstrated that wheat sprout extract, which has been shown to be antimutagenic towards benzo[a]pyrene (BP), reduced formation of BP metabolites by hepatic microsomes of either benzo[a]pyrene- or phenobarbital-treated rats as analyzed in high-pressure liquid chromatography (HPLC). Comparing the time dependence of profiles and values of BP metabolites, formed in experiments in which the same dose of wheat sprout extract was added to the incubation medium, it has been… CONTINUE READING


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