Mechanism of antifoaming action of simethicone

  title={Mechanism of antifoaming action of simethicone},
  author={Ljerka Bre{\vc}evi{\'c} and Ingrid Bo{\vs}an-Kilibarda and Franjo Strajnar},
  journal={Journal of Applied Toxicology},
The mechanism of the foam‐inhibiting action of simethicone, mainly used against flatulence, has been studied. Its effect on foaming systems containing synthetic gastric juice and a surface‐active substance (anionic surfactant, cationic surfactant, soap solution) was quantitated by measuring the surface tension, foam stability and initial foam density. The effect of simethicone on each of the examined systems was the result of the combination of two actions: the drainage of liquid from foam… Expand

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