Mechanism of analgesic action of intrathecal sufentanil.

  title={Mechanism of analgesic action of intrathecal sufentanil.},
  author={Fazeela Ferouz and Mark C. Norris},
  journal={Anesthesia and analgesia},
  volume={87 5},
We read the recent report by Gage et al. (1) with interest. Their results agree with our previously published study showing that hyperbaric intrathecal sufentanil injected in laboring women in the sitting position produces significantly less pain relief and pruritus than isobaric sufentanil (2). The authors conclude that the “addition of dextrose to intrathecal sufentanil limits the spread of adequate concentrations of sufentanil in the low thoracic region of the spinal cord” and, therefore… Expand

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