Mechanism of allosteric effects of ATP on the kinetics of P-type ATPases

  title={Mechanism of allosteric effects of ATP on the kinetics of P-type ATPases},
  author={Ronald J Clarke},
  journal={European Biophysics Journal},
The roles of allosteric effects of ATP and protein oligomerisation in the mechanisms of P-type ATPases belong to the most controversial and least well understood topics in the field. Recent crystal structural and kinetic data, however, now allow certain hypotheses to be definitely excluded and consistent hypotheses to be developed. The aim of this review is to critically discuss recent results and, in the light of them, to present a set of conclusions which could form the basis of future… CONTINUE READING
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Publications referenced by this paper.
Showing 1-10 of 125 references

Two gears of ion pumping by the Na,KATPase

  • RJ Clarke, DJ Kane
  • Biophys J 93:4187–4196
  • 2007
Highly Influential
14 Excerpts

Protomers of Na,K-ATPase from microsomes of duck salt gland are mostly monomeric: formation of higher oligomers does not modify molecular activity

  • DW Martin, J Maracek, S Scarlata, JR Sachs
  • Proc Natl Acad Sci USA 97:3195–3200
  • 2000
Highly Influential
4 Excerpts

Na,K-ATPase pump cycle

  • JE Mahaney, DD Thomas, JP Froehlich
  • Biophys J
  • 2004
Highly Influential
4 Excerpts

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