Mechanism of allosteric effects of ATP on the kinetics of P-type ATPases

@article{Clarke2009MechanismOA,
  title={Mechanism of allosteric effects of ATP on the kinetics of P-type ATPases},
  author={Ronald J Clarke},
  journal={European Biophysics Journal},
  year={2009},
  volume={39},
  pages={3-17}
}
The roles of allosteric effects of ATP and protein oligomerisation in the mechanisms of P-type ATPases belong to the most controversial and least well understood topics in the field. Recent crystal structural and kinetic data, however, now allow certain hypotheses to be definitely excluded and consistent hypotheses to be developed. The aim of this review is to critically discuss recent results and, in the light of them, to present a set of conclusions which could form the basis of future… CONTINUE READING
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