Mechanism of airway inflammation in asthma.

  title={Mechanism of airway inflammation in asthma.},
  author={William W. Busse and W F Calhoun and Jonathon D. Sedgwick},
  journal={The American review of respiratory disease},
  volume={147 6 Pt 2},
Airway inflammation has emerged as an important contributor to mechanisms of asthma. Furthermore, the presence of airway inflammation is present even in the absence of severe symptoms. To study the mechanisms by which bronchial inflammation can occur in asthma, a number of models have been developed including the airway response to antigen in allergic subjects. The pattern that has emerged from such studies indicates prompt pulmonary mast-cell activation and the apparent initiation of an… CONTINUE READING


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